selected Publications by PD Dr. rer. nat. Uta E. Höpken

Wichner K, Fischer A, Winter S, Tetzlaff S, Heimesaat MM, Bereswill S, Rehm A, Lipp M, Höpken UE
Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota.
Journal of Autoimmunity 2013; 47:58-72.
Schumann M, Winter S, Wichner K, May C, Kühl AA, Batra A, Siegmund B, Zeitz M, Schulzke JD, Lipp M, Höpken UE
CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis.
Mucosal Immunology 2012; 5(4):377-387.
Rehm A, Mensen A, Schradi K, Gerlach K, Winter S, Büchner G, Dörken B, Lipp M, Höpken UE
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Blood 2011; 118:1020-1033.
Herda S, Raczkowski F, Mittrücker H-W, Willimsky G, Gerlach K, Kühl, AA, Breiderhoff T, Willnow TE, Dörken B, Höpken UE, Rehm A
The sorting receptor Sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
Immunity 2012; 37:854-866.
Winter S, Rehm A, Wichner K, Scheel T, Batra A, Siegmund B, Berek C, Lipp M, Höpken UE
Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice.
Am. J. Pathol 2011; 179(2):754-765.
Rehm A, Mensen A, Schradi K, Gerlach K, Winter S, Büchner G, Dörken B , Lipp M, Höpken UE
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Blood 2011; 118(4):1020-1033.
Höpken UE, Winter S, Achtman AH, Krüger K, Lipp M
CCR7 regulates lymphocyte egress and recirculation through body cavities.
J. Leukoc. Biol 2010; 87:671-682.
Winter S, Aebischer A, Loddenkemper C, Räbel K, Hoffmann K, Meyer TF, Lipp M, Höpken UE
The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation.
J. Mol. Med 2010; 88(11):1169-1180.
van de Pavert SA, Goverse G, Vondenhoff MF, Beke P, Höpken UE, Lipp M, Niederreither K, Blomhoff R, Agace WW, Mebius R
CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.
Nature Immunology 2009; 10:1193-1199.
Rüder C, Höpken UE, Wolf J, Mittrücker HW, Engels B, Erdmann B, Wollenzin S, Uckert W, Dörken B, Rehm A
The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
J. Clin. Invest 2009; 119:2184-2203.

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Birgit Roeders

Charité – Universitätsmedizin Berlin

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